"Numbs the pain, but won't help serious wounds. Serious stuff. Also good for getting off the junk."

Methadone is a type of consumable item which restores a large amount of Vitality.

Item ListEdit

The following item lists contain this item Note: S = State of Decay Storyline; B= Breakdown; L= Lifeline



  • Methadone is among the most powerful health items in the game, along with Morphine and Homemade Painkiller.
  • Methadone is renamed to Extra Strength Painkillers in the Year One Edition of State of Decay

Real-life informationEdit

  • Methadone is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependence.

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